Swapnroop Drugs & Pharmaceuticals offers Brompheniramine Maleate API for pharmaceutical manufacturing, formulation development and research applications. Brompheniramine Maleate is an antihistamine belonging to the alkylamine class and is used for the symptomatic relief of allergic conditions.
Brompheniramine Maleate is the maleic acid salt of brompheniramine. It acts primarily as a histamine H1-receptor antagonist and has antiallergic, anticholinergic and sedative properties. It is commonly used in pharmaceutical preparations for allergic rhinitis, conjunctivitis and related allergic symptoms.
Brompheniramine Maleate has the molecular formula C20H23BrN2O4 and a molecular weight of approximately 435.3 g/mol. Its CAS number is 980-71-2. PubChem identifies Brompheniramine Maleate as the maleate salt of brompheniramine.
The parent compound Brompheniramine has the molecular formula C16H19BrN2, molecular weight 319.24 g/mol and CAS number 86-22-6.
Product Name: Brompheniramine Maleate
Chemical Name: Brompheniramine hydrogen maleate
CAS Number: 980-71-2
Molecular Formula: C20H23BrN2O4
Molecular Weight: 435.3 g/mol
Chemical Class: Alkylamine antihistamine / maleate salt
Therapeutic Category: Antihistamine / Antiallergic
Pharmacological Class: Histamine H1 receptor antagonist
Brompheniramine Maleate is used as an antihistamine for symptomatic relief of allergic conditions including allergic rhinitis and conjunctivitis. It is also used in combination pharmaceutical products for relief of cold and allergy symptoms.
Brompheniramine Maleate is a solid pharmaceutical substance. PubChem reports a molecular weight of 435.3 g/mol and a topological polar surface area of 90.7 Ų.
The free-base Brompheniramine is described as an oily liquid with slightly yellow color and a melting point below 25 °C, whereas the maleate salt has substantially different physical properties. Therefore, free-base physical-property data should not be substituted for Brompheniramine Maleate.
Appearance: White crystalline powder
Identification: Infrared absorption / chromatographic identification
Assay (HPLC): 98.0%–102.0% on dried basis
Loss on Drying: NMT 1.0%
Residue on Ignition: NMT 0.2%
Heavy Metals: NMT 20 ppm
pH (1% Solution): 4.0–6.0
Individual Impurity: NMT 0.5%
Total Impurities: NMT 2.0%
Water Content: NMT 1.0%
Specific Rotation: Applicable to the specified stereochemical material
Melting Point: Approximately 132–134 °C
Solubility: Soluble in water; soluble in alcohol
Brompheniramine Maleate API can be supplied in suitable pharmaceutical-grade packaging according to customer requirements, product quantity and applicable pharmaceutical handling requirements.
Applicable documentation may include Certificate of Analysis (CoA), product specification, safety documentation and other quality documents according to product grade and customer requirements.
Store Brompheniramine Maleate in a tightly closed container in a cool, dry and well-ventilated environment, protected from excessive moisture, heat and direct light. Follow the applicable product specification for exact storage conditions.
Swapnroop Drugs & Pharmaceuticals supports pharmaceutical customers with API sourcing and commercial supply requirements. Contact Swapnroop Drugs & Pharmaceuticals for Brompheniramine Maleate availability, specifications, documentation, packaging and commercial supply information.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification | IR / HPLC |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 1.0% |
| Residue on Ignition | NMT 0.2% |
| Heavy Metals | NMT 20 ppm |