Swapnroop Drugs & Pharmaceuticals offers Bromodiphenhydramine Hydrochloride API for pharmaceutical manufacturing, formulation development and research applications.
Bromodiphenhydramine Hydrochloride is the hydrochloride salt of bromodiphenhydramine, also known as bromazine. It is an ethanolamine antihistamine that acts primarily as a histamine H1-receptor antagonist and also possesses anticholinergic and sedative properties.
Bromodiphenhydramine Hydrochloride has the molecular formula C17H21BrClNO and a molecular weight of 370.7 g/mol. Its CAS number is 1808-12-4. USP identifies the substance as Ethanamine, 2-(4-bromophenyl)phenylmethoxy-N,N-dimethyl-, hydrochloride.
The parent compound Bromodiphenhydramine has CAS 118-23-0 and molecular formula C17H20BrNO, while the hydrochloride salt has CAS 1808-12-4 and molecular weight 370.71 g/mol.
Product Name: Bromodiphenhydramine Hydrochloride
Synonyms: Bromazine Hydrochloride; Bromodiphenhydramine HCl; Ambodryl
CAS Number: 1808-12-4
Molecular Formula: C17H21BrClNO
Molecular Weight: 370.71 g/mol
Chemical Class: Ethanolamine antihistamine
Therapeutic Category: Antihistamine / Antiallergic
Pharmacological Class: Histamine H1-receptor antagonist
Bromodiphenhydramine Hydrochloride has antihistamine and antiallergic properties. It has historically been used for the symptomatic treatment of allergic conditions and is associated with H1-receptor antagonism.
Bromodiphenhydramine Hydrochloride is a hydrochloride salt of bromodiphenhydramine. The substance has a molecular weight of 370.7 g/mol and is represented by the molecular formula C17H21BrClNO.
Appearance: White to almost white crystalline powder
Identification: Infrared absorption / chromatographic identification
Assay: 98.0%–101.0% on dried basis
Loss on Drying: 0.5% maximum
Residue on Ignition: 0.2% maximum
Heavy Metals: 20 ppm maximum
pH (1% Solution): 4.0–6.0
Individual Impurity: 0.5% maximum
Total Impurities: 2.0% maximum
Water Content: 0.5% maximum
Specific Rotation: Not applicable to the racemic material
Melting Point: Approximately 168–172 °C
Solubility: Soluble in water; soluble in alcohol
Bromodiphenhydramine Hydrochloride API can be supplied in suitable pharmaceutical-grade packaging according to customer requirements, product quantity and applicable pharmaceutical handling requirements.
Applicable documentation may include Certificate of Analysis (CoA), product specification, safety documentation and technical documentation according to product grade and customer requirements.
Store Bromodiphenhydramine Hydrochloride in a tightly closed container in a cool, dry and well-ventilated environment, protected from excessive moisture, heat and direct light. Follow applicable pharmaceutical storage requirements.
Swapnroop Drugs & Pharmaceuticals supports pharmaceutical customers with API sourcing and commercial supply requirements. Contact Swapnroop Drugs & Pharmaceuticals for Bromodiphenhydramine Hydrochloride availability, specifications, documentation, packaging and commercial supply information.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification | IR / HPLC |
| Assay (HPLC) | 98.0% – 101.0% |
| Loss on Drying | NMT 0.5% |
| Residue on Ignition | NMT 0.2% |
| Heavy Metals | NMT 20 ppm |