Brincidofovir API Manufacturer in India

Brincidofovir API

Brincidofovir is an orally bioavailable lipid-conjugated prodrug of cidofovir and an antiviral active pharmaceutical ingredient. It is also known as CMX001, HDP-cidofovir, and hexadecyloxypropyl-cidofovir. Its CAS number is 444805-28-1, with molecular formula C₂₇H₅₂N₃O₇P and molecular weight 561.69 g/mol.

Brincidofovir is a nucleotide analogue antiviral that is converted intracellularly to cidofovir and subsequently to the active metabolite cidofovir diphosphate. The FDA-approved product TEMBEXA is indicated for treatment of human smallpox disease.

Key Characteristics

• Chemical Name: Phosphonic acid, P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-, mono[3-(hexadecyloxy)propyl] ester
• CAS Number: 444805-28-1
• Molecular Formula: C₂₇H₅₂N₃O₇P
• Molecular Weight: 561.69 g/mol
• Appearance: White to off-white crystalline powder
• Form: Powder
• Water Solubility: Practically insoluble
• DMSO Solubility: 2 mg/mL, clear when warmed, for the cited research-grade material
• Synonyms: CMX001, CMX-001, HDP-Cidofovir, Hexadecyloxypropyl-cidofovir
• ATC Code: J05AB17

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