Bethanechol Chloride API Manufacturer in India

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Bethanechol Chloride API Manufacturer in India

Bethanechol Chloride is a synthetic choline carbamate and muscarinic cholinergic agonist used as a pharmaceutical active ingredient. It selectively stimulates muscarinic receptors without significant nicotinic activity.

Bethanechol Chloride is primarily used in pharmaceutical formulations for non-obstructive urinary retention and bladder atony. It has also been used for certain gastrointestinal motility disorders.

Product Overview

  • Product Name: Bethanechol Chloride
  • Common Name: Bethanechol
  • Synonyms: Carbamyl-β-methylcholine Chloride; (2-Carbamoyloxypropyl)trimethylammonium Chloride
  • API Form: Chloride salt
  • CAS Number: 590-63-6
  • Molecular Formula: C₇H₁₇ClN₂O₂
  • Molecular Weight: 196.68 g/mol
  • Category: Active Pharmaceutical Ingredient
  • Therapeutic Class: Parasympathomimetic / Cholinergic Agent
  • Pharmacological Class: Muscarinic receptor agonist
  • Physical Form: White crystalline powder / crystals
  • Nature: Hygroscopic
  • Stereochemistry: Racemic / (±)

PubChem identifies Bethanechol Chloride as the chloride salt of bethanechol and gives CAS 590-63-6, formula C₇H₁₇ClN₂O₂, and molecular weight approximately 196.67 g/mol.

3. PHARMACEUTICAL APPLICATIONS

Bethanechol Chloride is used in pharmaceutical formulations for:

  • Non-obstructive urinary retention
  • Postoperative urinary retention
  • Postpartum non-obstructive urinary retention
  • Neurogenic bladder atony
  • Increasing urinary bladder smooth-muscle tone
  • Selected gastrointestinal motility applications

Current clinical references identify urinary retention and bladder atony as principal therapeutic uses.

Detailed Specifications

Parameter Specification
Appearance White to off-white crystalline powder
Identification Conforms — IR / chromatographic identification
Assay (HPLC) 98.0% – 101.5% on dried basis
Heavy Metals NMT 30 ppm
pH (1% Solution) 5.5 – 6.5
Individual Impurity NMT 1.5%
Melting Point Approximately 214–218°C
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