Aspirin EC Micro Pellets (For Tableting) are pharmaceutical-grade enteric-coated multiparticulate pellets containing Aspirin (Acetylsalicylic Acid) as the active ingredient. Aspirin has CAS Number 50-78-2, molecular formula C₉H₈O₄, and molecular weight 180.16 g/mol.
These micro pellets are specifically designed for incorporation into tablet formulations. Compared with conventional larger pellets, micro-pellets can provide greater flexibility during blending and compression when developing multiparticulate tablets. The functional enteric coating is designed to provide resistance to acidic conditions followed by release under the specified gastrointestinal conditions.
A commercially documented Aspirin EC Micro Pellets (For Tableting) product is available at 65% w/w strength. This 65% value is also consistently listed in multiple commercial pharmaceutical pellet portfolios. It should be treated as the documented commercial reference strength; publish it as an SDP available strength only if it matches the current SDP specification or COA.
The micro-pellet format can be used for enteric-coated tablet development, multiparticulate tablets, compression-compatible formulations and pharmaceutical manufacturing. Important quality attributes include Aspirin loading, particle-size distribution, coating uniformity, acid resistance, mechanical properties during compression and dissolution performance.
Aspirin EC Micro Pellets can be incorporated into tablets where the individual pellet coating is designed to maintain enteric protection after the compression process.
Micro-pellets provide a multiparticulate approach for developing compressed oral dosage forms containing multiple coated units.
The product is specifically positioned for tableting, with particle size and mechanical properties considered during formulation and compression development.
Aspirin EC Micro Pellets can be used as a ready-to-process intermediate for formulation optimization and scale-up.
The pellets can be supplied in bulk according to the required active loading, particle-size distribution, coating and release specifications.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 1.0% |
| Residue on Ignition | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| pH (1% Solution) | 5.0 – 7.0 |
| Water Content | NMT 1.0% |