Pharmaceutical-Grade Aprepitant Immediate-Release Pellets for Oral Multiparticulate Formulations
Aprepitant IR Pellets are immediate-release pharmaceutical pellets containing Aprepitant as the active ingredient. Aprepitant has the molecular formula C₂₃H₂₁F₇N₄O₃, CAS Number 170729-80-3, and molecular weight approximately 534.4 g/mol.
Aprepitant is formulated in multiparticulate pellet systems to provide an immediate-release format suitable for oral dosage-form development and capsule-filling applications. Commercial pharmaceutical pellet references report 40% w/w Aprepitant IR Pellets, while some manufacturers also list 35% or 15% strengths.
For the SDP product page, the 40% w/w strength should be used only if it matches the SDP product specification/COA. Since the SDP product list provided earlier does not establish an Aprepitant strength, the finished-pellet assay should remain product-specific unless SDP confirms the strength.
Aprepitant IR Pellets can be used for:
Aprepitant IR Pellets can be supplied in suitable pharmaceutical packaging according to the applicable product and batch requirements. Final strength, particle-size distribution, moisture, density, friability and other release parameters should be confirmed against the current product specification.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 95.0% – 105.0% |
| Loss on Drying | NMT 0.5% |
| Residue on Ignition | NMT 0.1% |
| Heavy Metals | NMT 10 ppm |
| pH (1% Solution) | 5.0 – 7.0 |
| Individual Impurity | NMT 0.5% |
| Water Content | NMT 0.5% |