Acetyl Tetrapeptide-2 is a synthetic acetylated tetrapeptide used in cosmetic formulations, particularly in advanced skin-care products focused on skin conditioning, regeneration and anti-aging cosmetic concepts. It is also known by the names Peptigravity and Thymulen 4 in ingredient and technical literature.
The peptide has the sequence Ac-Lys-Asp-Val-Tyr-OH, abbreviated KDVY. Its CAS number is 757942-88-4, molecular formula is C₂₆H₃₉N₅O₉, and molecular weight is approximately 565.6 g/mol.
Acetyl Tetrapeptide-2 is incorporated into cosmetic formulations as an active peptide ingredient. A commercial formulation containing Acetyl Tetrapeptide-2, for example, is positioned as an anti-aging active for skin-care applications.
Acetyl Tetrapeptide-2 is an N-acetylated tetrapeptide consisting of lysine, aspartic acid, valine and tyrosine residues.
Key characteristics include:
| Parameter | Details |
|---|---|
| Product Name | Acetyl Tetrapeptide-2 |
| INCI Name | Acetyl Tetrapeptide-2 |
| Common Names | Peptigravity, Thymulen 4 |
| Chemical Name | N-acetyl-L-lysyl-L-alpha-aspartyl-L-valyl-L-tyrosine |
| Peptide Sequence | Ac-Lys-Asp-Val-Tyr-OH |
| Sequence Abbreviation | KDVY |
| Chemical Class | Acetylated Tetrapeptide |
| CAS Number | 757942-88-4 |
| Molecular Formula | C₂₆H₃₉N₅O₉ |
| Molecular Weight | 565.6 g/mol |
| Appearance | Grade-dependent; typically supplied as a peptide powder or formulated solution |
| Main Application | Skin Care |
| Typical Product Positioning | Anti-Aging, Skin Conditioning |
| Main Formats | Serums, Creams, Lotions, Leave-On Skin Care |
PubChem records CAS 757942-88-4, molecular formula C₂₆H₃₉N₅O₉, molecular weight 565.6 g/mol, and the sequence Ac-Lys-Asp-Val-Tyr-OH.
CAS No.: 757942-88-4
INCI Name: Acetyl Tetrapeptide-2
Common Names: Peptigravity; Thymulen 4
Peptide Sequence: Ac-Lys-Asp-Val-Tyr-OH
Sequence: KDVY
Molecular Formula: C₂₆H₃₉N₅O₉
Molecular Weight: approximately 565.6 g/mol.
Ac-Lys-Asp-Val-Tyr-OH
The four amino-acid residues are:
The complete structure is N-acetyl-L-lysyl-L-alpha-aspartyl-L-valyl-L-tyrosine.
Acetyl Tetrapeptide-2 is used in cosmetic formulations designed around:
Commercial ingredient information describes Thymulen 4 as a biomimetic peptide and an anti-aging active for skin-care applications.
For SDP content, claims should remain cosmetic in nature and should be supported by the specific ingredient supplier's technical documentation and applicable cosmetic regulations.
Acetyl Tetrapeptide-2 can be incorporated into suitable peptide-based facial serum formulations.
Potential applications include:
Potential applications include:
It can also be considered for suitable:
Important factors include:
Solubility and incorporation characteristics can vary according to the raw-material form and commercial grade. The supplier's TDS should be followed for the recommended solvent system and incorporation procedure.
Avoid unnecessary exposure to high temperatures during manufacturing. Peptide ingredients should generally be incorporated according to the supplier's recommended processing conditions.
The final formulation pH should be selected according to the stability requirements of the specific grade and the complete formulation system.
Storage conditions are grade-specific. For the SDP CMS, the final storage statement should be taken from the actual commercial-grade SDS/TDS rather than using an assumed universal temperature.
Acetyl Tetrapeptide-2 can be considered for:
Acetyl Tetrapeptide-2 is a synthetic acetylated tetrapeptide with the sequence Ac-Lys-Asp-Val-Tyr-OH.
The CAS number is 757942-88-4.
The INCI name is Acetyl Tetrapeptide-2.
The peptide sequence is Ac-Lys-Asp-Val-Tyr-OH, abbreviated KDVY.
It is also listed under Peptigravity and Thymulen 4.
It is used as a cosmetic peptide active in skin-care formulations, particularly anti-aging and skin-conditioning product concepts.
Yes. It can be incorporated into suitable peptide-based serum formulations.
Yes. It can be incorporated into suitable creams, moisturizers and other leave-on formulations.
The molecular formula is C₂₆H₃₉N₅O₉.
The molecular weight is approximately 565.6 g/mol.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white powder |